What is the "chelating" technology?
The word Chelate comes from the Greek word Chele, which means crab claws. Chelates are like minerals in crab claws and have high stability.
In 1930, the first chelate, EDTA (ethylenediaminetetraacetic acid) chelate, was first synthesized in Germany for the treatment of patients with heavy metal poisoning. Thereafter, the chelate was continuously researched, developed, and applied to treatment. Arteriosclerosis disease, etc. After the emergence of amino acid chelate in the 1970s, it has been widely used due to its good bioavailability.
In 1987, the American Food Management Association (AAFCO) defined amino acid chelates as: a metal ion dissociated from a soluble salt reacts with an amino acid in a ratio of 1 mole of metal to 1 to 3 moles of amino acid to form a covalent chelate structure. product. The average molecular weight of the hydrolyzed amino acid must be controlled to about 150, while the molecular weight of the entire product does not exceed 800.
An amino acid molecule contains an amino or nitrogen group on one side and an organic acid or carboxyl group on the other side. When the formation medium is basic and there is no H+ interference, the carboxyl and amino groups on both sides can be bonded to the metal atom at different positions. Form a chelate together. Amino acid chelated metals have a relatively high stability constant of 107-12. While citrate and ascorbate form very weak chelating bonds 102-4, EDTA (ethylenediaminetetraacetic acid) and its derivatives form strong chelates with metals with high stability constants 1016-28 . Tannin and ascorbic acid decompose before being absorbed by biological tissues, forming a positive-valent metal ion, which is difficult to be absorbed. The chelate formed by EDTA and its derivatives is very stable, and it will completely decompose through the physiological system of plants and animals (including humans), so EDTA is often removed from the physiological system as a cleaning agent. Metal ions. The amino acid chelate metal has sufficient stability in the living body, and its chelation structure can be destroyed in the living body, and the metal minerals and amino acids are absorbed by the physiological tissues in different places.
In the human body, there are many small intestinal villus cells as the delivery system of amino acids. When amino acids enter the human small intestine, the small intestine villi cells actively absorb amino acids and transport them to various physiological tissues of the body for absorption and utilization. Amino acid chelate in the human body follows the same active transport mechanism as amino acids, and is actively absorbed by the human body.
Amino acid sequestration minerals are easily absorbed by the body due to their low molecular weight and true covalent chemical structure. The absorption and utilization efficiency of amino acid chelated calcium is 60-80% higher than that of common calcium salt and 60% higher than that of milk. The bioavailability of amino acid chelated zinc is 200-300% higher than that of zinc salt and 200% higher than that of methyl pyridinium. Amino acid chelated magnesium is 250% higher than inorganic magnesium. At the same time, it has been found that amino acid chelate chromium, copper, iron and manganese can effectively improve bioavailability. The bioavailability of amino acid chelated iron is 3.8 times higher than that of iron sulfate and 3.6 times higher than that of iron oxide. The bioavailability of amino acid chelated copper is more than three times that of copper oxide, almost four times that of copper sulfate and six times that of copper carbonate.
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